Anti-HIC1 antibody produced in rabbit
SIGMA/AV32623 - affinity isolated antibody
Synonym: Anti-Hypermethylated in cancer 1
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.5 mg - 1 mg/mL |
conjugate | unconjugated |
form | buffered aqueous solution |
mol wt | 74 kDa |
NCBI accession no. | NP_001091672 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | western blot: suitable |
UniProt accession no. | Q14526-2 |
Application: | Rabbit Anti-HIC1 antibody can be used for western blot applications at a concentration of 0.25μg/ml. |
Biochem/physiol Actions: | HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | HIC1 is a tumor suppressor that interacts with SIRT1 to regulate p53-depenedent responses to DNA damage. Rabbit Anti-HIC1 antibody recognizes human, mouse, and rat HIC1. |
Immunogen: | Synthetic peptide directed towards the N terminal region of human HIC1 |
Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Sequence: | Synthetic peptide located within the following region: ALCASERRCSPLCGLDLSKKSPPGS |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |