Anti-HMG20A (AB2) antibody produced in rabbit
SIGMA/AV32759 - affinity isolated antibody
Synonym: Anti-FLJ10739; Anti-HMGX1; Anti-High-mobility group 20A
Product Type: Chemical
Immunoblotting Cell Type: 293T (Cat. No. AV32759). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type 293T
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 40 kDa |
| NCBI accession no. | NP_060670   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, dog, guinea pig, horse, human |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9NP66 |
| Application: | Rabbit Anti-HMG20A (AB2) antibody can be used for western blot applications at 1.25 μg/ml. |
| Biochem/physiol Actions: | HMG20A plays a role in neuronal differentiation as chromatin-associated protein. HMG20A acts as inhibitor of HMG20B. HMG20A overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. HMG20A involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | HMG20A is a homeobox gene that is expressed ubiquitously. Studies in CHO-K1 cells have reported that it interacts with the poxvirus protein, CP77, and modulates its dissociation from the genome of vaccinia virus. Rabbit Anti-HMG20A (AB2) antibody recognizes bovine, human, mouse, rat, and canine HMG20A. |
| Immunogen: | Synthetic peptide directed towards the middle region of human HMG20A |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: RKTQDRQKGKSHRQDAARQATHDHE |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |