Anti-P2RX2 (AB1) antibody produced in rabbit
SIGMA/AV35259 - IgG fraction of antiserum
Synonym: Anti-Purinergic receptor P2X, ligand-gated ion channel, 2
Product Type: Chemical
Immunohistochemistry Anti-P2RX2 (ab1): Cat. No. AV35259: Immunohistochemistry of P2RX2 in Human Kidney tissue with P2RX2 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV35259). Lanes 1. Antibody dilution (concentration) 0.6 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 42 kDa |
| NCBI accession no. | NP_733782   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q9UBL9-5 |
| Application: | Rabbit Anti-P2RX2 is suitable for western blot (0.6 μg/ml) and IHC (4-8 μg/ml) applications. |
| Biochem/physiol Actions: | P2RX2 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | P2RX2 (P2X2) is a purinoceptor that functions as an ATP-gated ion channel. The ectodomain movements of this receptor have been analyzed using disulphide locking. In propyl-methanethiosulfona Rabbit Anti-P2RX2 antibody recognizes human and bovine P2RX2. |
| Immunogen: | Synthetic peptide directed towards the middle region of human P2RX2 |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Sequence: | Synthetic peptide located within the following region: LIKNSIHYPKFHFSKGNIADRTDGY |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |