Fetuin from fetal bovine serum
SIGMA/F3004 - lyophilized powder
Synonym: Fetuin from fetal calf serum
CAS Number: 9014-81-7
EC Number: 232-762-7
MDL Number: MFCD00131055
Product Type: Chemical
biological source | bovine serum (fetal) |
form | lyophilized powder |
impurities | ~0.2% free N-acetylneuraminic acid |
Quality Level | 200 |
storage temp. | 2-8°C |
technique(s) | HPLC: suitable |
MALDI-MS: suitable | |
UniProt accession no. | Q58D62 |
Application: | Fetuin from fetal bovine serum has been used: • as a standard glycoprotein in matrix-assisted laser desorption/ionization-mas • as a ligand in carbohydrate binding assay of pertussis toxin vaccine • in the synthesis of fetuin-A conjugated gold nanoparticles (F-GNPs) for drug carrier studies |
Biochem/physiol Actions: | In humans, polymorphism in the fetuin gene is implicated in type 2 diabetes mellitus and modulates adipocyte functionality. Elevated level of fetuin is observed in obesity and nonalcoholic fatty liver diseases (NAFLD). Fetuin is a potential marker in clinical diagnosis of metabolic disorders. |
General description: | Fetuin is an abundant glycosylated protein from fetal bovine serum and functions as a transport and storage protein. It is also called the α2-Heremans-Schmid glycoprotein (AHSG) and corresponds to a molecular weight of 64 kDa. It belongs to the statin family and is synthesized principally in the liver and partially in the kidneys, placenta and the tongue. |
Packaging: | 1 g in glass bottle |
Packaging: | 25, 100, 250 mg in glass bottle |
Preparation Note: | Further processing of F2379 by gel filtration. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |