EMD-87580
SIGMA/SML1828 - ≥98% (HPLC)
Synonym: EMD87580; N-
CAS Number: 187870-78-6
Empirical Formula (Hill Notation): C11H15N3O5S2
Molecular Weight: 333.38
Linear Formula: C11H15N3O5S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 |
SMILES string | NC(NC(C1=CC(S(=O)(C)=O)=C |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Application: | EMD-87580 has been used as a selective and potent sodium-hydrogen antiporter 1 (NHE-1) inhibitor in cardiac ventricular myocytes to test its effect on the hypertrophic response. |
Biochem/physiol Actions: | EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. EMD-87580 has shown cardioprotective effects, and has been investigated as a possible treatment for Duchenne′s muscular dystrophy. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |