Harmane

ALDRICH/103276 - 98%

Synonym: 1-Methyl-9H-pyrido[3,4-b]indole; 2-Methyl-β-carboline; Aribine

CAS Number: 486-84-0
Empirical Formula (Hill Notation): C₁₂H₁₀N₂
Molecular Weight: 182.22
EC Number: 207-642-2
MDL Number: MFCD00004957
Linear Formula: C₁₂H₁₀N₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-103276-1G	1 g	$254.00 1/EAAdd To Favorites	Add To Favorites

assay	98%
drug control	stupéfiant (France)
InChI	1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3
InChI key	PSFDQSOCUJVVGF-UHFFFAOYSA-N
mp	235-238 °C (lit.)
Quality Level	100
SMILES string	Cc1nccc2c3ccccc3[nH]c12
solubility	methanol: soluble 50mg/ml

Application:	• Harmane was used in trace level determination of harmane by planar chromatography coupled with (tandem) mass spectrometry. • It was used to study interactions of norharman and harman with DNA. • It may be used as matrix for analysis of cyclodextrins and for sulfated oligosaccharides in combination with DHB as co-matrix.
Biochem/physiol Actions:	I₁ imidazoline binding site agonist.
General description:	• Harmane is a potent tremor-producing β-carboline alkaloid and neurotoxin. • It is major representative of heterocyclic aromatic amines, a group of mutagenic and carcinogenic substances which are formed in meat from the precursors creatine, creatinine, amino acids and sugars during the heating at high temperatures. • Blood harmane concentration is elevated in essential tremor, late-life neurological disease.
Packaging:	1 g in glass bottle
Preparation Note:	Harmane dissolves in methanol at a concentration of 50mg/ml to form a clear, colourless to yellow solution.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable