Pentafluorophenol
ALDRICH/103799 - ReagentPlus®, ≥99%
Synonym: 2,3,4,5,6-
CAS Number: 771-61-9
Empirical Formula (Hill Notation): C6HF5O
Molecular Weight: 184.06
EC Number: 212-235-8
MDL Number: MFCD00002156
Linear Formula: C6F5OH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 103799-100G.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 103799-5G.
| application(s) | peptide synthesis |
| assay | ≥99% |
| bp | 143 °C (lit.) |
| form | solid |
| functional group | fluoro |
| InChI | 1S/C6HF5O/c7-1-2(8)4(10)6 |
| InChI key | XBNGYFFABRKICK-UHFFFAOYSA |
| mp | 34-36 °C (lit.) |
| product line | ReagentPlus® |
| Quality Level | 100  |
| SMILES string | Oc1c(F)c(F)c(F)c(F)c1F |
| Application: | Pentafluorophenol can be used as a reactant to synthesize pentafluorophenyl esters from: • N-protected amino acid in the presence of dicyclohexylcarbodiimide and ethyl acetate. • t-Butoxycarbonyl-L-alanylglycinein the presence of 1-ethyl-(3-dimethylaminop • Aliphatic dicarboxylic acids in the presence of pyridine, diisopropylcarbodiimide, and acetonitrile. It can also be used as a reactant to synthesize pentafluorophenyl formate which can be used as a formylating agent in organic synthesis. |
| General description: | Pentafluorophenol is widely used as a precursor in both solution and solid-phase peptide synthesis. It is also involved in the preparation of aromatic fluoro derivatives. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 5, 10, 100 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 161.6 °F - closed cup |
| Flash Point(C) | 72 °C - closed cup |
| Purity | ≥99% |
| bp | 143 °C (lit.) |
| mp | 34-36 °C (lit.) |
| UNSPSC | 12352104 |