Chloroacetyl chloride
ALDRICH/104493 - 98%
Synonym: Chloroacetic chloride
CAS Number: 79-04-9
Empirical Formula (Hill Notation): C2H2Cl2O
Molecular Weight: 112.94
EC Number: 201-171-6
MDL Number: MFCD00000725
Linear Formula: ClCH2COCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 104493-100G.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 104493-500G.
| assay | 98% |
| bp | 105-106 °C (lit.) |
| density | 1.418 g/mL at 25 °C (lit.) |
| InChI | 1S/C2H2Cl2O/c3-1-2(4)5/h1 |
| InChI key | VGCXGMAHQTYDJK-UHFFFAOYSA |
| mp | −22 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | ClCC(Cl)=O |
| vapor density | 3.9 (vs air) |
| vapor pressure | 60 mmHg ( 41.5 °C) |
| Application: | Chloroacetyl chloride can be used for chloroacetylation and chemical modification of poly(glycidyl methacrylate). Chloroacetyl chloride was used to study the in vitro metabolism of chloroacetamide herbicides by rat and human liver microsomes. Chloroacetyl chloride was used in the synthesis of some novel quinoline derivatives having antileishmanial activity. |
| General description: | Chloroacetyl chloride is used as a chlorinating agent, acylating agent, precursor to monochloroketene, and as a building block for cyclization. Chloroacetyl chloride causes the acylation of cyano-pyrazoline during the synthesis of secondary amine-substituted cyano-pyrazoline derivatives. |
| Packaging: | 5, 100, 500 g in glass bottle |
| Symbol |     GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 + H311 + H331 - H314 - H372 - H400 |
| Precautionary statements | P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P314 |
| Hazard Codes | T,C,N |
| Risk Statements | 14-23/24/25-29-35-48/23-50 |
| Safety Statements | 7/8-9-26-36/37/39-45-61 |
| RIDADR | UN 1752 8(6.1) / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | 212.0 °F - closed cup |
| Flash Point(C) | 100 °C - closed cup |
| Supplemental Hazard Statements | EUH014 - EUH029 - EUH071 |
| Purity | 98% |
| bp | 105-106 °C (lit.) |
| mp | −22 °C (lit.) |
| Density | 1.418 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |