Fmoc isothiocyanate

ALDRICH/10919 - ≥98.0% (CHN)

Synonym: 9-Fluorenylmethoxycarbonyl isothiocyanate; 9-Fluorenylmethyl isothiocyanatoformate

CAS Number: 199915-38-3
Empirical Formula (Hill Notation): C₁₆H₁₁NO₂S
Molecular Weight: 281.33
MDL Number: MFCD01861169
Linear Formula: C₁₆H₁₁NO₂S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-10919-1G	1 g	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites
45-10919-5G	5 g	$862.00 1/EAAdd To Favorites	Add To Favorites

application(s)	peptide synthesis
assay	≥85% (coupling to amines)
	≥98.0% (CHN)
fluorescence	λ_ex 264 nm; λ_em 313 nm
functional group	amine
	Fmoc
	isothiocyanate
InChI	1S/C16H11NO2S/c18-16(17-10-20)19-9-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9H2
InChI key	DHMYULZVFHHEHE-UHFFFAOYSA-N
Quality Level	100
SMILES string	O=C(OCC1c2ccccc2-c3ccccc13)N=C=S
solubility	ethanol: soluble
storage temp.	−20°C

Application:	Fmoc isothiocyanate can be used: • As a starting material in the preparation of biologically relevant pharmacophores named N-aryl-N′-carboalkoxy guanidines. • In one of the intermediate steps for the synthesis of N-aryl-N-thiazolyl derivatives. • To synthesize cyclic isothiourea derivatives as potent neuropeptide Y (NPY) Y1 receptor antagonists. • To prepare 2-aminothiazoles, aminobenz-imidazole conjugated thiazoles, and thiazole derived cyclopeptides.
Other Notes:	Reagent for the synthesis of substituted thioureas from amines
Packaging:	1 g in poly tube
Packaging:	5 g in poly bottle

Symbol	GHS05,GHS07
Signal word	Danger
Hazard statements	H315 - H318 - H335
Precautionary statements	P261 - P280 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	37/38-41
Safety Statements	36/39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥85% (coupling to amines); ≥98.0% (CHN)
Storage Temp.	−20°C
UNSPSC	12352005