Mechlorethamine hydrochloride
ALDRICH/122564 - 98%
Synonym: 2-Chloro-N-(2-chloroethyl)-N-methylethanamine; N-
CAS Number: 55-86-7
Empirical Formula (Hill Notation): C5H11Cl2N · HCl
Molecular Weight: 192.51
EC Number: 200-246-0
MDL Number: MFCD00012517
Linear Formula: (ClCH2CH2)2NCH3·HCl
Product Type: Chemical
assay | 98% |
form | solid |
InChI | 1S/C5H11Cl2N.ClH/c1-8(4-2 |
InChI key | QZIQJVCYUQZDIR-UHFFFAOYSA |
mp | 108-111 °C (lit.) |
Quality Level | 100 ![]() |
SMILES string | Cl.CN(CCCl)CCCl |
solubility | alcohol: soluble |
H2O: very soluble |
Application: | Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard. |
Biochem/physiol Actions: | Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats. |
Packaging: | 5, 25 g in glass bottle |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H300 + H310 - H314 - H340 - H350 - H360D |
Precautionary statements | P201 - P260 - P280 - P301 + P310 + P330 - P303 + P361 + P353 - P305 + P351 + P338 |
Hazard Codes | T+ |
Risk Statements | 45-46-61-27/28-34 |
Safety Statements | 53-36/37/39-45 |
RIDADR | UN 2928 8(6.1) / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 98% |
mp | 108-111 °C (lit.) |
UNSPSC | 12352100 |