N-Hydroxysuccinimide

ALDRICH/130672 - 98%

Synonym: 1-Hydroxy-2,5-pyrrolidinedione; HOSu; NHS

CAS Number: 6066-82-6
Empirical Formula (Hill Notation): C₄H₅NO₃
Molecular Weight: 115.09
EC Number: 228-001-3
MDL Number: MFCD00005516
Linear Formula: C₄H₅NO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-130672-5G	5 g	$25.80 1/EAAdd To Favorites		Add To Favorites
45-130672-25G	25 g	$53.70 1/EAAdd To Favorites		Add To Favorites
45-130672-100G	100 g	$124.00 1/EAAdd To Favorites		Add To Favorites
45-130672-250G	250 g	$295.00 1/EAAdd To Favorites		Add To Favorites
45-130672-1KG	1 kg	$764.00 1/EAAdd To Favorites		Add To Favorites
45-130672-5KG	5 kg	$0.00 1/EA CALL FOR PRICEAdd To Favorites		Add To Favorites

assay	98%
form	solid
functional group	imide
InChI	1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
InChI key	NQTADLQHYWFPDB-UHFFFAOYSA-N
mp	95-98 °C (lit.)
Quality Level	200
SMILES string	ON1C(=O)CCC1=O

Application:	N-Hydroxysuccinimide can be used in the synthesis of N-hydroxysuccinimide ester via dehydration reaction in the presence of dicyclohexylcarbodiimide in carboxylic acid.
Application:	N-Hydroxysuccinimide has been used in the synthesis of intermediates such as: • N • -succinimidyl 3-(di-tert-butylfluorosilyl)benzoate • 4-[2,2-bis[(p-tolylsulfonyl)-methyl] acetyl]benzoic acid-NHS ester • N-succinimidyl 3-iodobenzoate It has also been used in a protocol for the surface modification of microchannels of a microfluidic-integrated surface plasmon resonance (SPR) platform for the detection and quantification of bacterial pathogens.
Application:	Additive used in the carbodiimide method for improved amidations and peptide couplings.
Packaging:	1 kg in poly bottle
Packaging:	5 kg in poly drum
Packaging:	5, 25, 100, 250 g in poly bottle