Trimethyl phosphate
ALDRICH/132195 - 97%
Synonym: TMP; TMPA; TMPO
CAS Number: 512-56-1
Empirical Formula (Hill Notation): C3H9O4P
Molecular Weight: 140.07
EC Number: 208-144-8
MDL Number: MFCD00008348
Linear Formula: (CH3O)3PO
Product Type: Chemical
| assay | 97% |
| bp | 197 °C (lit.) |
| density | 1.197 g/mL at 25 °C (lit.) |
| form | liquid |
| functional group | phosphate |
| InChI | 1S/C3H9O4P/c1-5-8(4,6-2)7 |
| InChI key | WVLBCYQITXONBZ-UHFFFAOYSA |
| mp | −46 °C (lit.) |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | COP(=O)(OC)OC |
| Application: | Trimethyl phosphate can be used as a methylating agent for the: • Solvent-free o-methylation of phenolic compounds to synthesize methyl aryl ethers. • S-methylation of aryl/alkyl thiols to synthesize S-methylated product in the presence of Ca(OH)2 as a base. |
| General description: | Trimethyl phosphate is an excellent dipolar aprotic solvent that is used as a methylating agent and acid scavenger in many organic transformations. |
| Packaging: | 1 kg in glass bottle |
| Packaging: | 250 g in glass bottle |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H340 - H351 |
| Precautionary statements | P201 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T,Xi |
| Risk Statements | 46-22-36-38-40 |
| Safety Statements | 53-26-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 302.0 °F - closed cup |
| Flash Point(C) | 150 °C - closed cup |
| Purity | 97% |
| bp | 197 °C (lit.) |
| mp | −46 °C (lit.) |
| Density | 1.197 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |



