Cyclohexyl isocyanide

ALDRICH/133302 - 98%

Synonym: Isocyanocyclohexane

CAS Number: 931-53-3
Empirical Formula (Hill Notation): C₇H₁₁N
Molecular Weight: 109.17
EC Number: 213-238-7
MDL Number: MFCD00003839
Linear Formula: C₆H₁₁NC
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-133302-1G	1 g	$55.70 1/EAAdd To Favorites		Add To Favorites
45-133302-5G	5 g	$128.00 1/EAAdd To Favorites		Add To Favorites

assay	98%
density	0.878 g/mL at 25 °C (lit.)
form	liquid
InChI	1S/C7H11N/c1-8-7-5-3-2-4-6-7/h7H,2-6H2
InChI key	XYZMOVWWVXBHDP-UHFFFAOYSA-N
Quality Level	100
refractive index	n20/D 1.45 (lit.)
SMILES string	[C-]#[N+]C1CCCCC1
storage temp.	2-8°C

Application:	• Isocyanide in coordination chemistry: The study on mixed "2 + 1" tricarbonyl dithiocarbamate complexes highlights Cyclohexyl isocyanide′s role as an effective monodentate ligand, contributing to advancements in radiopharmaceutical applications using Re, Tc, and Re isotopes (Shegani et al., 2021 ). • Organic synthesis reagent in vascular treatments: The article discusses the use of Cyclohexyl isocyanide in modifying the endocannabinoid system, emphasizing its potential in developing treatments for conditions like hypertension through biochemical pathway modulation (Baranowska-Kuczko et al., 2021 ). • Chemical process optimization in dye decolorization: Cyclohexyl isocyanide plays a crucial role in the covalent immobilization of enzymes used for the decolorization of textile dyes, demonstrating its utility in environmental chemistry and industrial applications related to pollution control (Salami et al., 2018 ). • Application in nanocellulose modification: Demonstrates the versatility of Cyclohexyl isocyanide in nanotechnology by facilitating the covalent attachment of temperature-responsive polymers to cellulose nanofibrils, enhancing the material′s properties for use in smart textiles and responsive materials (Khine et al., 2018 ).
General description:	Cyclohexyl isocyanide reacts with dimethyl acetylenedicarboxylate to give a mixture of cyclopenta[b]pyridine derivatives, azaspirononatriene derivative and the azabicyclononatriene. It reacts with dialkyl acetylenedicarboxylates to form 1:1 intermediate which on facile addition to 1-benzylisatin and tryptantrin yields highly functionalized novel unsaturated γ-spiroiminolactones.
Packaging:	1, 5 g in ampule