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(1R,2S)-(−)-Ephedrine

ALDRICH/134910 - 98%

Synonym: (−)-Ephedrine; (1R,2S)-(−)-α-(1-Methylaminoethyl)benzyl alcohol; (1R,2S)-(−)-2-Methylamino-1-phenyl-1-propanol; L-α-(1-Methylaminoethyl)benzyl alcohol

CAS Number: 299-42-3
Empirical Formula (Hill Notation): C10H15NO
Molecular Weight: 165.23
EC Number: 206-080-5
MDL Number: MFCD00064257
Linear Formula: C6H5CH[CH(NHCH3)CH3]OH
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-134910-25G 25 g
 $466.00
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45-134910-100G 100 g
 $1340.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 134910-100G

 

assay 98%
bp 255 °C (lit.)
density 1.124 g/mL at 25 °C (lit.)
form solid
functional group amine
  hydroxyl
  phenyl
InChI 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1
InChI key KWGRBVOPPLSCSI-WPRPVWTQSA-N
mp 37-39 °C (lit.)
optical activity [α]21/D −41°, c = 5 in 1 M HCl
Quality Level 200 
SMILES string CN[C@@H](C)[C@H](O)c1ccccc1
storage temp. 2-8°C
Application: (1R,2S)-(-)-Ephedrine can be used in the preparation of optically active phosphine-phosphonite ligands and chirally-substituted cyclopentadienyl (Cp) ligands. It reacts with phosphorus trichloride to form (2R,4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine. It can also act as a chiral resolving agent for (±)-mandelic acid.
Application: Versatile chiral synthon, employed in catalysis and in the preparation of optically pure sulfoxides and oxazolidines.
General description: (1R,2S)-(-)-Ephedrine, a chiral β-amino alcohol, is commonly used as a chiral auxiliary in asymmetric synthesis. It undergoes reduction to form (+)-methamphetamine.
Packaging: 25, 100 g in glass bottle
Purity 98%
bp 255 °C (lit.)
mp 37-39 °C (lit.)
Density 1.124 g/mL at 25 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 12352116

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