(1R,2S)-(−)-Ephedrine
ALDRICH/134910 - 98%
Synonym: (−)-Ephedrine; (1R,2S)-(−)-α-(1-Methylaminoethyl)benzyl alcohol; (1R,2S)-(−)-2-Methylamino-1-phenyl-1-propanol; L-α-(1-Methylaminoethyl)benzyl alcohol
CAS Number: 299-42-3
Empirical Formula (Hill Notation): C10H15NO
Molecular Weight: 165.23
EC Number: 206-080-5
MDL Number: MFCD00064257
Linear Formula: C6H5CH[CH(NHCH3)CH3]OH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 134910-100G
| assay | 98% |
| bp | 255 °C (lit.) |
| density | 1.124 g/mL at 25 °C (lit.) |
| form | solid |
| InChI | 1S/C10H15NO/c1-8(11-2)10( |
| InChI key | KWGRBVOPPLSCSI-WPRPVWTQSA |
| mp | 37-39 °C (lit.) |
| optical activity | [α]21/D −41°, c = 5 in 1 M HCl |
| Quality Level | 200  |
| SMILES string | CN[C@@H](C)[C@H](O)c1cccc |
| storage temp. | 2-8°C |
| Application: | (1R,2S)-(-)-Ephedrine can be used in the preparation of optically active phosphine-phosphonite ligands and chirally-substituted cyclopentadienyl (Cp) ligands. It reacts with phosphorus trichloride to form (2R,4S,5R)-2-chloro-3,4-dimethyl-5 |
| Application: | Versatile chiral synthon, employed in catalysis and in the preparation of optically pure sulfoxides and oxazolidines. |
| General description: | (1R,2S)-(-)-Ephedrine, a chiral β-amino alcohol, is commonly used as a chiral auxiliary in asymmetric synthesis. It undergoes reduction to form (+)-methamphetamine. |
| Packaging: | 25, 100 g in glass bottle |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H314 - H317 |
| Precautionary statements | P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 186.8 °F - closed cup |
| Flash Point(C) | 86 °C - closed cup |
| Purity | 98% |
| bp | 255 °C (lit.) |
| mp | 37-39 °C (lit.) |
| Density | 1.124 g/mL at 25 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352116 |