Phenyl isothiocyanate

ALDRICH/139742 - reagent grade, 98%

Synonym: PITC

CAS Number: 103-72-0
Empirical Formula (Hill Notation): C₇H₅NS
Molecular Weight: 135.19
EC Number: 203-138-1
MDL Number: MFCD00004798
Linear Formula: C₆H₅NCS
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-139742-100G	100 g	$76.40 1/EAAdd To Favorites		Add To Favorites
45-139742-500G	500 g	$246.00 1/EAAdd To Favorites		Add To Favorites

assay	98%
bp	218 °C (lit.)
density	1.132 g/mL at 20 °C (lit.)
form	liquid
functional group	isothiocyanate
grade	reagent grade
InChI	1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H
InChI key	QKFJKGMPGYROCL-UHFFFAOYSA-N
mp	−21 °C (lit.)
Quality Level	200
refractive index	n20/D 1.6515 (lit.)
SMILES string	S=C=Nc1ccccc1
solubility	water: insoluble

Application:	Derivatizing reagent for primary and secondary amines. Used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC.
Application:	Phenyl isothiocyanate may be employed as a derivatization reagent for high-performance liquid chromatographic (HPLC) analysis of various amphetamine derivatives in body fluids for forensic purposes. Phenyl isothiocyanate (PIT) modified with polyethylene glycol (PEG), can be used as a reagent for PEGylation of protein using human serum albumin as a model protein.
General description:	Phenyl isothiocyanate is an aromatic isothiocyanate. It participates in dehydration reactions of alcohols. It is widely used for synthesis of various biologically important heterocyclic compounds.
Packaging:	5, 100, 500 g in glass bottle

Symbol	GHS05,GHS06,GHS08
Signal word	Danger
Hazard statements	H301 - H314 - H317 - H334
Precautionary statements	P261 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Codes	T,N
Risk Statements	25-34-42/43-51/53
Safety Statements	23-26-36/37/39-45-61
RIDADR	UN 2927 8(6.1) / PGII
WGK Germany	WGK 3
Flash Point(F)	190.4 °F - closed cup
Flash Point(C)	88 °C - closed cup