Chlorosulfonyl isocyanate

ALDRICH/142662 - 98%

Synonym: N-Carbonylsulfamyl chloride; CSI

CAS Number: 1189-71-5
Empirical Formula (Hill Notation): CClNO₃S
Molecular Weight: 141.53
EC Number: 214-715-2
MDL Number: MFCD00011608
Linear Formula: ClSO₂NCO
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-142662-25G	25 g	$69.90 1/EAAdd To Favorites		Add To Favorites
45-142662-100G	100 g	$159.00 1/EAAdd To Favorites		Add To Favorites
45-142662-1KG	1 kg	$1280.00 1/EAAdd To Favorites		Add To Favorites

assay	98%
bp	107 °C (lit.)
density	1.626 g/mL at 25 °C (lit.)
form	liquid
InChI	1S/CClNO3S/c2-7(5,6)3-1-4
InChI key	WRJWRGBVPUUDLA-UHFFFAOYSA-N
mp	−44 °C (lit.)
Quality Level	200
refractive index	n20/D 1.447 (lit.)
SMILES string	ClS(=O)(=O)N=C=O
storage temp.	2-8°C
vapor pressure	5.57 psi ( 20 °C)

Application:	• Chlorosulfonyl isocyanate was used in synthesis and biochemical characterization of new class of membrane-associated glycosyltransferase inhibitors. • It is synthetically versatile reagent and was used in the preparation of amides, lactams and triazocinones. • It was employed in regio- and diastereoselective introduction of a protected amino group in synthesis of chiral, polyhydroxylated piperidines. • It was used as reagent during the synthesis of novel sulfamides.
Application:	Employed in a regio- and diastereoselective introduction of a protected amino group in a synthesis of chiral, polyhydroxylated piperidines. Generation of ureas from amino groups in a synthesis of benzimidazolones.
General description:	Chlorosulfonyl isocyanate is classified as an isocyanate and is widely used as a reagent in sulfonylation and carbamoylation reactions.Chlorosulfonyl isocyanate reacts with hydrocarbon alkenes via stepwise dipolar pathway to give N-chlorosulfonyl-β-lactams.
Packaging:	1 kg in glass bottle
Packaging:	25, 100 g in glass bottle

Symbol	GHS05,GHS07,GHS08
Signal word	Danger
Hazard statements	H302 - H314 - H317 - H334
Precautionary statements	P261 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Codes	C
Risk Statements	14-22-34-42
Safety Statements	23-26-30-36/37/39-45
RIDADR	UN 3265 8 / PGII
WGK Germany	WGK 3
Flash Point(F)	> 230.0 °F
Flash Point(C)	> 110 °C
Supplemental Hazard Statements	EUH014