Trimethylacetic anhydride

ALDRICH/143502 - 99%

Synonym: Pivalic anhydride; 2,2-Dimethylpropionic anhydride

CAS Number: 1538-75-6
Empirical Formula (Hill Notation): C₁₀H₁₈O₃
Molecular Weight: 186.25
EC Number: 216-263-1
MDL Number: MFCD00008842
Linear Formula: [(CH₃)₃CCO]₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-143502-25G	25 g	$60.80 1/EAAdd To Favorites		Add To Favorites
45-143502-100G	100 g	$181.00 1/EAAdd To Favorites		Add To Favorites

assay	99%
bp	193 °C (lit.)
density	0.918 g/mL at 25 °C (lit.)
form	liquid
functional group	anhydride
	ester
InChI	1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3
InChI key	PGZVFRAEAAXREB-UHFFFAOYSA-N
Quality Level	200
refractive index	n20/D 1.409 (lit.)
SMILES string	CC(C)(C)C(=O)OC(=O)C(C)(C)C

Application:	Acylation and esterification reagent for anilines and phenols, respectively.
Application:	Trimethylacetic anhydride was used: • in solid-phase oligonucleotide synthesis • in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid • as acylation and esterification reagent for anilines • as acylation and esterification reagent for phenols
Packaging:	25, 100 g in glass bottle

Symbol	GHS02,GHS05
Signal word	Danger
Hazard statements	H226 - H314
Precautionary statements	P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
Hazard Codes	C
Risk Statements	34
Safety Statements	26-36/37/39-45
RIDADR	UN 2920 3(8) / PGII
WGK Germany	WGK 3
Flash Point(F)	134.6 °F - closed cup
Flash Point(C)	57 °C - closed cup