5-Hydroxyindole-2-carboxylic acid

ALDRICH/143510 - ≥96.5%

Synonym: NSC 117338

CAS Number: 21598-06-1
Empirical Formula (Hill Notation): C₉H₇NO₃
Molecular Weight: 177.16
EC Number: 244-468-6
MDL Number: MFCD00005615
Linear Formula: C₉H₇NO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-143510-1G	1 g	$0.00 1/EA CALL FOR PRICEAdd To Favorites		Add To Favorites
45-143510-5G	5 g	$458.00 1/EAAdd To Favorites		Add To Favorites

assay	≥96.5%
form	powder
functional group	carboxylic acid
InChI	1S/C9H7NO3/c11-6-1-2-7-5(3-6)4-8(10-7)9(12)13/h1-4,10-11H,(H,12,13)
InChI key	BIMHWDJKNOMNLD-UHFFFAOYSA-N
mp	249 °C (dec.) (lit.)
Quality Level	200
SMILES string	Oc1ccc2[nH]c(cc2c1)C(O)=O
solubility	chloroform/ethanol (1:1): soluble 50 mg/mL, clear to slightly hazy, yellow to brown

Application:	• Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents • Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors • Reactant for preparation of melanins as novel nature-inspired radioprotectors • Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity • Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription 3 (Stat3) • Reactant for preparation of oxadiazole analogs as nonpeptidic SH2 inhibitors of tyrosine kinase ZAP-70
Application:	5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine.
General description:	5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO₄ yields pyrrole-2,3,5-tricarboxylic acid.
Packaging:	1, 5 g in glass bottle