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N,N-Bis(phosphonomethyl)glycine

ALDRICH/15149 - ≥98.0% (T)

Synonym: N-(Carboxymethyl)iminodi(methylphosphinic acid); Glyphosine

CAS Number: 2439-99-8
Empirical Formula (Hill Notation): C4H11NO8P2
Molecular Weight: 263.08
EC Number: 219-468-4
MDL Number: MFCD00056670
Linear Formula: C4H11NO8P2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-15149-10G 10 g
$169.00
1/EA
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45-15149-50G 50 g
$567.00
1/EA
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assay ≥98.0% (T)
functional group amine
  carboxylic acid
InChI 1S/C4H11NO8P2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
InChI key OXHDYFKENBXUEM-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=P(CN(CP(O)(O)=O)CC(O)=O)(O)O
Application: Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89

Anti-diabetic; delay onset of diabetes in non-obese NOD mice

Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.†
Biochem/physiol Actions: Anti-diabetic; delay onset of diabetes in non-obese NOD mice
General description: N,N-Bis(phosphonomethyl)glycine was present in the ligand bound to human apotransferrin.
Packaging: 10, 50 g in poly bottle
Symbol GHS05  GHS05
Signal word Danger
Hazard statements H318
Precautionary statements P280 - P305 + P351 + P338 + P310
Hazard Codes Xi
Risk Statements 41
Safety Statements 26
RIDADR UN 3261 8 / PGIII
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.0% (T)
UNSPSC 12352100

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