1-Hydroxybenzotriazole hydrate
ALDRICH/157260 - wetted with not less than 14 wt. % water, 98% dry basis
Synonym: HOBt Hydrate
CAS Number: 123333-53-9
Empirical Formula (Hill Notation): C6H5N3O · xH2O
Molecular Weight: 135.12 (anhydrous basis)
EC Number: 219-989-7
Linear Formula: C6H5N3O · xH2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 157260-250G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 157260-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 157260-25G
| application(s) | peptide synthesis |
| assay | 98% dry basis |
| form | solid |
| InChI | 1S/C6H5N3O.H2O/c10-9-6-4- |
| InChI key | PJUPKRYGDFTMTM-UHFFFAOYSA |
| mp | 155-158 °C (lit.) |
| quality | synthesis grade |
| Quality Level | 200  |
| reaction suitability | reaction type: Addition Reactions |
| SMILES string | [H]O[H].On1nnc2ccccc12 |
| Application: | 1-Hydroxybenzotriazole hydrate can be used as a reagent:• To synthesize β-peptides via microwave-assisted amino acid coupling. • In the spot synthesis of glycopeptides. It can also be used as a deprotection agent for the removal of Fmoc (9-fluorenylmethoxycarbon |
| General description: | 1-Hydroxybenzotriazole hydrate is a derivative of benzotriazole primarily used as a coupling reagent in peptide synthesis. |
| Packaging: | 25, 100, 250 g in glass bottle |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H207 - H319 - H412 |
| Precautionary statements | P210 - P212 - P230 - P233 - P280 - P370 + P380 + P375 - P501 |
| Hazard Codes | F |
| Risk Statements | 1-11-44 |
| Safety Statements | 26-37-60 |
| RIDADR | UN3474 - class 4.1 - PG 1 - 1-Hydroxybenzotriazole, monohydrate |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH044 |
| Purity | 98% dry basis |
| mp | 155-158 °C (lit.) |
| UNSPSC | 12352000 |