5-(4-Hydroxyphenyl)-5-phenylhydantoin

ALDRICH/161543 - 98%

Synonym: 4-Hydroxydiphenylhydantoin; p-Hydroxyphenytoin; NSC 156081

CAS Number: 2784-27-2
Empirical Formula (Hill Notation): C₁₅H₁₂N₂O₃
Molecular Weight: 268.27
EC Number: 220-492-2
MDL Number: MFCD00005262
Linear Formula: C₁₅H₁₂N₂O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-161543-1G	1 g	$0.00 1/EA CALL FOR PRICE	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
form	solid
InChI	1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)
InChI key	XEEDURHPFVXALT-UHFFFAOYSA-N
mp	>300 °C (lit.)
Quality Level	100
SMILES string	Oc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3
solubility	soluble 50 mg/mL, clear, colorless to faintly yellow (DMF:MeOH(2:1))

Application:	5-(4-Hydroxyphenyl)-5-phenylhydantoin was used in enantiomeric separation of chiral pharmaceuticals using a teicoplanin chiral stationary phase by aqueous and non-aqueous packed capillary electrochromatography. It was used as internal standard in determination of phenylbutazone and its metabolite oxyphenbutazone in human plasma by GLC.
Application:	Reactant for activation of hydroxylated metabolites of carbamazepine and phenytoin Used in studies investigating Transport across the human placenta barrier Effects on cellular glucose transport
General description:	5-(4-Hydroxyphenyl)-5-phenylhydantoin is the major metabolite of phenytoin.
Other Notes:	Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 161543.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Packaging:	1 g in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98%
mp	>300 °C (lit.)
UNSPSC	12352100

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