Methylboronic acid
ALDRICH/165336 - 97%
Synonym: Methaneboronic acid
CAS Number: 13061-96-6
Empirical Formula (Hill Notation): CH5BO2
Molecular Weight: 59.86
MDL Number: MFCD00002105
Linear Formula: CH3B(OH)2
Product Type: Chemical
| assay | 97% |
| form | solid |
| InChI | 1S/CH5BO2/c1-2(3)4/h3-4H, |
| InChI key | KTMKRRPZPWUYKK-UHFFFAOYSA |
| mp | 91-94 °C (lit.) |
| Quality Level | 100  |
| SMILES string | CB(O)O |
| Application: | Methylboronic acid can be used as a reagent: • In the palladium-catalyzed Stille and Suzuki-Miyaura cross-couplings. • In the microwave-heated heterogeneous palladium (Pd)-catalytized reactions. • In ruthenium (Ru)-catalyzed silylation reactions • To prepare bis(aminotropone) titanium (Ti) catalysts for ethylene polymerizations. • In the enantioselective asymmetric bromoaminocyclization and bromoaminocyclization using amino-thiocarbamate catalysts. • To prepare common building blocks for pharmaceuticals and agrochemicals. • To prepare chrysin analogs by Suzuki-Miyaura coupling reactions. • To prepare casein kinase I inhibitors. • In the divergent C-H functionalizations directed by sulfonamide pharmacophores in drug discovery. • In the synthesis of unsymmetrical monosulfides from disulfides via copper-catalyzed coupling with boronic acids. • In a palladium-catalyzed coupling with enol tosylates. • For derivatizing many carbohydrates and biologically active compounds for GLC analysis. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 91-94 °C (lit.) |
| UNSPSC | 12352103 |