Borane tetrahydrofuran complex solution
ALDRICH/176192 - 1.0 M in THF
Synonym: Borane-THF (1:1); Boron hydride (BH3)-THF (1:1); Tetrahydrofuran-
CAS Number: 14044-65-6
Empirical Formula (Hill Notation): C4H11BO
Molecular Weight: 85.94
MDL Number: MFCD00012429
Linear Formula: BH3OC4H8
Product Type: Chemical
25 mL Sure/Seal™ Packaging
| concentration | 1.0 M in THF |
| contains | <0.005 M sodium borohydride as stabilizer |
| density | 0.898 g/mL at 25 °C |
| InChI | 1S/C4H8O.BH3/c1-2-4-5-3-1 |
| InChI key | RMCYTHFAWCWRFA-UHFFFAOYSA |
| Quality Level | 200  |
| reaction suitability | reagent type: reductant |
| SMILES string | B.C1CCOC1 |
| storage temp. | 2-8°C |
| Application: | New, Safer, NIMBA-Stabilized BH3 THF Solutions |
| Application: | BH3-THF can be used as a reducing agent for the reduction of various functional groups such as carboxylic acids, aldehydes, ketones, esters, acid chlorides, nitriles, epoxides, amides, lactones, oximes, and imines into corresponding alcohols and amines. Grignard reagents, arylmercury, arylthalium, and allyl and propargyllithium compounds react with BH3−THF to give organoboranes, which can be oxidized to the corresponding alcohols, phenols, and 1,3-diols. It can also be used: • To synthesize the chiral borane catalyst, which is used in the enantioselective halo-aldol reaction. • To prepare 9-unsubstituted acridines by reduction of corresponding acridones. • To reduce nylon surface amide groups to secondary amines. |
| General description: | Borane tetrahydrofuran complex (BH3-THF) is widely used as a reducing agent in organic synthesis. It is also used as a reagent in hydroboration reactions. |
| Legal Information: | Sure/Seal is a trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 4×25, 100, 800 mL in Sure/Seal™ |
| Packaging: | The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product. |
| Symbol |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H260 - H302 - H318 - H335 - H351 |
| Precautionary statements | P201 - P210 - P231 + P232 - P280 - P305 + P351 + P338 + P310 - P308 + P313 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-14/15-19-22-37/38-41 |
| Safety Statements | 16-26-33-43 |
| RIDADR | UN 3399A 4.3(3) / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | 1.4 °F - closed cup |
| Flash Point(C) | -17 °C - closed cup |
| Supplemental Hazard Statements | EUH018 - EUH019 |
| Density | 0.898 g/mL at 25 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352005 |