Ethyl chloroformate
ALDRICH/185892 - 97%
Synonym: Chloroformic acid ethyl ester
CAS Number: 541-41-3
Empirical Formula (Hill Notation): C3H5ClO2
Molecular Weight: 108.52
EC Number: 208-778-5
MDL Number: MFCD00000644
Linear Formula: ClCOOC2H5
Product Type: Chemical
assay | 97% |
autoignition temp. | 842 °F |
bp | 93 °C (lit.) |
density | 1.135 g/mL at 25 °C (lit.) |
form | liquid |
InChI | 1S/C3H5ClO2/c1-2-6-3(4)5/ |
InChI key | RIFGWPKJUGCATF-UHFFFAOYSA |
mp | −81 °C (lit.) |
Quality Level | 200 |
refractive index | n |
SMILES string | CCOC(Cl)=O |
solubility | alcohol: miscible |
benzene: miscible | |
chloroform: miscible | |
diethyl ether: miscible | |
water: insoluble | |
vapor density | 3.74 (vs air) |
vapor pressure | 3.42 psi ( 20 °C) |
Application: | • Ethyl chloroformate was used in the synthesis of nitrile oxides. • It was used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. • It was used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography. • It was used as derivatization reagent in an enantiomeric analysis of amino acids by two-dimensional gas chromatography. • It was also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. |
Packaging: | 100, 500 g in Sure/Seal™ |
Packaging: | 2 kg in poly bottle |
Packaging: | 5 g in glass bottle |
Packaging: | Derivatization reagent employed in an enantiomeric analysis of amino acids by two-dimensional gas chromatography. Also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. |
Symbol | GHS02,GHS05,GHS06 |
Signal word | Danger |
Hazard statements | H225 - H290 - H302 - H314 - H330 |
Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | F,T+,N |
Risk Statements | 11-22-26-34-50 |
Safety Statements | 9-16-26-28-33-36/37/39-45-61 |
RIDADR | UN1182 - class 6.1 - PG 1 - Ethyl chloroformate |
WGK Germany | WGK 1 |
Flash Point(F) | 60.8 °F |
Flash Point(C) | 16 °C |
Purity | 97% |
bp | 93 °C (lit.) |
mp | −81 °C (lit.) |
Density | 1.135 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12352100 |