Methylmagnesium chloride solution
ALDRICH/189901 - 3.0 M in THF
Synonym: Chloromethylmagnesium; Methyl magnesium chloride; Methylmagnesiumchloride
CAS Number: 676-58-4
Empirical Formula (Hill Notation): CH3ClMg
Molecular Weight: 74.79
MDL Number: MFCD00000468
Linear Formula: CH3MgCl
Product Type: Chemical
autoignition temp. | 609 °F |
concentration | 3.0 M in THF |
density | 1.013 g/mL at 25 °C |
InChI | 1S/CH3.ClH.Mg/h1H3;1H;/q; |
InChI key | RQNMYNYHBQQZSP-UHFFFAOYSA |
Quality Level | 200 |
reaction suitability | reaction type: Grignard Reaction |
SMILES string | C[Mg]Cl |
Application: | Methylmagnesium chloride solution (3 M in THF) undergoes 1,3-addition with dialdose derived nitrones to form N-benzylhydroxylamines. The reductive cleavage of the N-O bond of these N-benzylhydroxylamines results in N-benzylaminosugars, which are key moieties of bioactive compounds. It can also react with Garner type aldehydes to form the corresponding secondary alcohols. |
Legal Information: | Sure/Seal is a trademark of Sigma-Aldrich Co. LLC |
Packaging: | 4×25, 100, 800 mL in Sure/Seal™ |
Packaging: | 8, 18 L in Kilo-Lab™ |
Packaging: | The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product. |
Packaging: | View returnable container options . |
Symbol | GHS02,GHS05,GHS07,GHS08 |
Signal word | Danger |
Hazard statements | H225 - H260 - H302 - H314 - H335 - H336 - H351 |
Precautionary statements | P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | F,C |
Risk Statements | 11-14-19-34-37 |
Safety Statements | 16-26-36/37/39-45 |
RIDADR | UN 3399BC 4.3(3) / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | 1.0 °F - closed cup |
Flash Point(C) | -17.2 °C - closed cup |
Supplemental Hazard Statements | EUH014 - EUH019 |
Density | 1.013 g/mL at 25 °C |
UNSPSC | 12352103 |