12-Crown-4
ALDRICH/194905 - 98%
Synonym: 1,4,7,10-
CAS Number: 294-93-9
Empirical Formula (Hill Notation): C8H16O4
Molecular Weight: 176.21
EC Number: 206-036-5
MDL Number: MFCD00005103
Linear Formula: C8H16O4
Product Type: Chemical
| assay | 98% |
| bp | 61-70 °C/0.5 mmHg (lit.) |
| density | 1.089 g/mL at 25 °C (lit.) |
| form | liquid |
| InChI | 1S/C8H16O4/c1-2-10-5-6-12 |
| InChI key | XQQZRZQVBFHBHL-UHFFFAOYSA |
| mp | 16 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | C1COCCOCCOCCO1 |
| Application: | 12-Crown-4 can be used as: • A promoter in the synthesis of poly(diethylsiloxane) (PDES) from monomer hexaethylcyclotrisiloxane using NaOH as a catalyst via anionic ring-opening polymerization. • As an additive in the preparation of triarylmethane derivatives by palladium-catalyzed cross coupling reaction of aryl bromides with diarylmethane derivatives. • A phase transfer catalyst in organic synthesis. |
| General description: | 12-Crown-4 is a crown ether generally used as a ligand in coordination chemistry. It is also known as lithium ionophore because of its strong chelating property specific to lithium cation. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H330 |
| Precautionary statements | P304 + P340 + P310 |
| Hazard Codes | T+ |
| Risk Statements | 26 |
| Safety Statements | 28-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 235.4 °F - closed cup |
| Flash Point(C) | 113 °C - closed cup |
| Purity | 98% |
| bp | 61-70 °C/0.5 mmHg (lit.) |
| mp | 16 °C (lit.) |
| Density | 1.089 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352005 |