O-tert-Butylhydroxylamine hydrochloride
ALDRICH/20023 - ≥99.0% (AT)
Synonym: 2-
CAS Number: 39684-28-1
Empirical Formula (Hill Notation): C4H11NO · HCl
Molecular Weight: 125.60
EC Number: 254-590-1
MDL Number: MFCD00043272
Linear Formula: (CH3)3CONH2 · HCl
Product Type: Chemical
| assay | ≥99.0% (AT) |
| form | solid |
| InChI | 1S/C4H11NO.ClH/c1-4(2,3)6 |
| InChI key | ZBDXGNXNXXPKJI-UHFFFAOYSA |
| mp | ~155 °C (dec.) |
| Quality Level | 200  |
| SMILES string | Cl.CC(C)(C)ON |
| solubility | H2O: soluble 0.5 g/10 mL |
| Application: | O-tert-Butylhydroxylamine hydrochloride was used in the synthesis of N-methyl-O-tert-butylhydroxylamine hydrochloride. It was also used in the preparation of N-tert-butoxyamino acids as substrates for the unambiguous synthesis of N-hydroxy peptides. |
| Application: | Reactant involved in synthesis of biologically active molecules including: • CGS 25966 derivatives for use as MMP inhibitors • Imidazolidinedione derivatives for use as antimalarial treatments • Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists • Rab proteins for isoprenylation and geranylgeranylation inhibition Reactant involved in: • Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents • Double allylic alkylation of indole-2-hydroxamates • SN2 substitution reactions at amide nitrogens • Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H228 |
| Precautionary statements | P210 |
| Hazard Codes | F |
| Risk Statements | 11 |
| RIDADR | UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., H |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (AT) |
| mp | ~155 °C (dec.) |
| UNSPSC | 12352100 |