2,2-Dimethyl-1,3-dioxane-4,6-dione

ALDRICH/210145 - 98%

Synonym: Malonic acid cyclic isopropylidene ester; Meldrum’s acid; cycl-Isopropylidene malonate

CAS Number: 2033-24-1
Empirical Formula (Hill Notation): C₆H₈O₄
Molecular Weight: 144.13
EC Number: 217-992-8
MDL Number: MFCD00006638
Linear Formula: C₆H₈O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-210145-10G	10 g	$31.80 1/EA	Add To Favorites
45-210145-25G	25 g	$57.30 1/EA	Add To Favorites
45-210145-100G	100 g	$135.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
form	solid
functional group	ester
	ketal
InChI	1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3
InChI key	GXHFUVWIGNLZSC-UHFFFAOYSA-N
mp	92-96 °C (lit.)
Quality Level	200
SMILES string	CC1(C)OC(=O)CC(=O)O1
solubility	dioxane: soluble 5%, clear to very slightly hazy, colorless to faintly yellow
storage temp.	2-8°C

Application:	2,2-Dimethyl-1,3-dioxane-4,6-dione was used in the synthesis of: • macrocyclic β-keto lactone • 4-pyridyl-substituted heterocycles • 2-substituted indoles • isofraxidin.
General description:	2,2-Dimethyl-1,3-dioxane-4,6-dione (Meldrum′s acid) is widely used in organic synthesis, especially for multiple C-C bond formations due to its adequate acidity (pK_a 4.83) and steric rigidity. Knoevenagel condensation reaction between aldehydes and Meldrum′s acid are accelerated in ionic liquids. Meldrum′s acid is used as a valuable starting material to synthesize heterocycles and as intermediates in organic synthesis reactions.
Packaging:	10, 25, 100 g in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98%
mp	92-96 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	12352100

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