α-(4-Pyridyl N-oxide)-N-tert-butylnitrone
ALDRICH/215430 - 99%
Synonym: N-
CAS Number: 66893-81-0
Empirical Formula (Hill Notation): C10H14N2O2
Molecular Weight: 194.23
EC Number: 266-512-3
MDL Number: MFCD00041022
Linear Formula: C10H14N2O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 215430-1G
| assay | 99% |
| form | solid |
| functional group | amine |
| InChI | 1S/C10H14N2O2/c1-10(2,3)1 |
| InChI key | RNRMWTCECDHNQU-XYOKQWHBSA |
| mp | 183-185 °C (lit.) |
| Quality Level | 200  |
| SMILES string | CC(C)(C)[N+]([O-])=C/c1c |
| solubility | water: soluble 10 mg/mL, clear, colorless to faintly yellow |
| Application: | Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN. |
| Application: | α-(4-Pyridyl N-oxide)-N-tert-butylnitrone was used as spin trapping agent to detect: • the formation of hydroxyl radical adducts during decomposition of hydrogen peroxide in the presence of nickel (II) oligopeptides • hydroxyl radicals and selenide radical anions |
| Packaging: | 1 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99% |
| mp | 183-185 °C (lit.) |
| UNSPSC | 12352100 |