CDI
ALDRICH/21860 - ≥97.0% (T)
Synonym: 1,1′-Carbonyldiimidazole
CAS Number: 530-62-1
Empirical Formula (Hill Notation): C7H6N4O
Molecular Weight: 162.15
EC Number: 208-488-9
MDL Number: MFCD00005286
Linear Formula: C7H6N4O
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥97.0% (T) |
| form | solid |
| InChI | 1S/C7H6N4O/c12-7(10-3-1-8 |
| InChI key | PFKFTWBEEFSNDU-UHFFFAOYSA |
| mp | 115-122 °C |
| 117-122 °C (lit.) | |
| Quality Level | 200  |
| reaction suitability | reaction type: Carbonylations |
| SMILES string | O=C(n1ccnc1)n2ccnc2 |
| storage temp. | 2-8°C |
| Application: | CDI (1,1′-Carbonyldiimidazole • In the activation of malonic acid derivatives to prepare carbonyl imidazoles by mild decarboxylation. • In the activation of cellulose membranes for the development of immunosensors. • In the synthesis of substituted 1,3-oxazolo[4,5-d] pyridazinones. • As a reagent for the conversion of various hydroxamic acids to isocyanates by Lossen rearrangement. • In the synthesis of 1,3,4-oxadiazole derivatives , and peptide thioesters in water. • As an acylation agent for the synthesis of carbamates. |
| General description: | CDI serves as a powerful coupling reagent in peptide synthesis and organic chemistry. |
| Other Notes: | Reactive reagent for the activation of acids as imidazolides: synthesis of esters, amides, ketones etc. Reagent for immobilizing enzymes and affinity ligands; Carbonyl-transfer reagent for the synthesis of various heterocycles, some recent applications |
| Packaging: | 5, 25, 100 g in glass bottle |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H314 |
| Precautionary statements | P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 22-34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3263 8 / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97.0% (T) |
| mp | 115-122 °C; 117-122 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352115 |