N-Hydroxymaleimide
ALDRICH/226351 - 97%
Synonym: 1-
CAS Number: 4814-74-8
Empirical Formula (Hill Notation): C4H3NO3
Molecular Weight: 113.07
EC Number: 225-385-4
MDL Number: MFCD00005501
Linear Formula: C4H3NO3
Product Type: Chemical
application(s) | peptide synthesis |
assay | 97% |
form | solid |
InChI | 1S/C4H3NO3/c6-3-1-2-4(7)5 |
InChI key | BUXKULRFRATXSI-UHFFFAOYSA |
mp | 130-133 °C (dec.) (lit.) |
Quality Level | 200 |
reaction suitability | reaction type: Addition Reactions |
SMILES string | ON1C(=O)C=CC1=O |
Application: | N-Hydroxymaleimide can be used as an oxidant to generate N-hydroxy anilines in situ, which serve as key intermediates in the selective coupling reaction of N-substituted anilines with hydroxylamine derivatives, for the efficient synthesis of aromatic oximes. |
General description: | N-Hydroxymaleimide (NHMI) is an organic compound that is widely used as an oxidizing agent in organic synthesis. It is frequently used to selectively oxidize thiols to disulfides and in the synthesis of α, β-unsaturated carbonyl compounds. It can also act as a Michael acceptor and is used in the synthesis of peptides and proteins. |
Packaging: | 1 g in glass bottle |
Symbol | GHS05 |
Signal word | Danger |
Hazard statements | H314 |
Precautionary statements | P280 - P305 + P351 + P338 - P310 |
Hazard Codes | C |
Risk Statements | 34 |
Safety Statements | 26-36/37/39-45 |
RIDADR | UN 3261 8 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 97% |
mp | 130-133 °C (dec.) (lit.) |
UNSPSC | 12352005 |