Isopropylmagnesium chloride solution
ALDRICH/230111 - 2.0 M in THF
Synonym: Chloro 1-methylethyl magnesium; Chloroisopropylmagnesium; Isopropylmagnesium chloride; iPrMgCl
CAS Number: 1068-55-9
Empirical Formula (Hill Notation): C3H7ClMg
Molecular Weight: 102.85
MDL Number: MFCD00000466
Linear Formula: (CH3)2CHMgCl
Product Type: Chemical
25 mL Sure/Seal™ Packaging
4×100 Slip-cover Can
Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.
Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.
| concentration | 2.0 M in THF |
| density | 0.975 g/mL at 25 °C |
| InChI | 1S/C3H7.ClH.Mg/c1-3-2;;/h |
| InChI key | GPIBKUJXKCEZOH-UHFFFAOYSA |
| Quality Level | 200  |
| reaction suitability | reaction type: Grignard Reaction |
| SMILES string | CC(C)[Mg]Cl |
| Application: | Isopropylmagnesium chloride solution (2.0 M in THF) can be used as a reagent to synthesize: • 2,6-Diiodobenzaldehyde derivatives via regioselective metal-iodine exchange of 5-substituted 1,2,3-triiodobenzene in the presence of ethyl formate as a formylating agent. • Arene and heteroarene sulfonamides from aryl and heteroaryl bromides via the formation of corresponding Grignard reagents. • Symmetrical pyridyl monoselenides by treating with bromo/iodopyridines followed by quenching with selenyl chloride, SeCl2. |
| General description: | Isopropylmagnesium chloride is a highly reactive organomagnesium halide formed by the reaction of magnesium metal with isopropyl chloride. It is used in the Grignard reaction to form new carbon-carbon bonds. |
| Legal Information: | Sure/Seal is a trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 2.5 L in Sure/Seal™ |
| Packaging: | 4×25, 100, 4×100, 800 mL in Sure/Seal™ |
| Packaging: | The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product. |
| Symbol |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H260 - H314 - H335 - H336 - H351 |
| Precautionary statements | P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | F,C |
| Risk Statements | 11-14/15-19-34-37 |
| Safety Statements | 9-16-26-36/37/39-43-45 |
| RIDADR | UN 3399BC 4.3(3) / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 1.4 °F - closed cup |
| Flash Point(C) | -17 °C - closed cup |
| Supplemental Hazard Statements | EUH014 - EUH019 |
| Density | 0.975 g/mL at 25 °C |
| UNSPSC | 12352103 |