n-Butyllithium solution
ALDRICH/230715 - 11.0 M in hexanes
Synonym: n-BuLi; Butyl lithium; Butyllithium solution; Lithium-1-butanide
CAS Number: 109-72-8
Empirical Formula (Hill Notation): C4H9Li
Molecular Weight: 64.06
MDL Number: MFCD00009414
Linear Formula: CH3(CH2)3Li
Product Type: Chemical
concentration | 11.0 M in hexanes |
density | 0.761 g/mL at 25 °C |
form | liquid |
InChI | 1S/C4H9.Li/c1-3-4-2;/h1,3 |
InChI key | MZRVEZGGRBJDDB-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | [Li]CCCC |
storage temp. | 2-8°C |
Application: | n-BuLi can be used as a reagent for lithium-halogen exchange reactions. Synthesis of various other useful reagents such as lithium diisopropylamide (LDA) and diphenylphosphine is prepared by in situ reaction with n-BuLi . In the polymerization of dienes, it can be employed as an initiator. |
General description: | n-Butyllithium (n-BuLi) is an organolithium reagent commonly used as a strong base to form corresponding lithium salts by the deprotonation of nitrogen, oxygen, phosphorus, and carbon acids. Heterocyclic compounds, such as furans, thiophenes, oxazoles, pyrroles, etc, can be lithiated α to the ring heteroatom using n?BuLi. These lithiated salts reacting in situ with alkyl halides to obtain useful organic compounds by the formation of the C-C bond. |
Legal Information: | Sure/Seal is a trademark of Sigma-Aldrich Co. LLC |
Packaging: | 4×25, 100 mL in Sure/Seal™ |
Packaging: | The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product. |
Symbol | GHS02,GHS05,GHS07,GHS08,GHS09 |
Signal word | Danger |
Hazard statements | H225 - H250 - H260 - H304 - H314 - H336 - H361f - H373 - H411 |
Precautionary statements | P210 - P231 + P232 - P280 - P301 + P310 + P331 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 |
Hazard Codes | F,C,N |
Risk Statements | 11-14/15-17-34-48/20-51/53-62-65-67 |
Safety Statements | 26-36/37/39-43-45-61-62 |
RIDADR | UN 3394 4.3(4.2) / PGI |
WGK Germany | WGK 2 |
Flash Point(F) | -7.6 °F - closed cup |
Flash Point(C) | -22 °C - closed cup |
Supplemental Hazard Statements | EUH014 |
Density | 0.761 g/mL at 25 °C |
Storage Temp. | 2-8°C |
UNSPSC | 12352103 |