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Chloromethyl chloroformate

ALDRICH/23181 - ≥98.0% (GC)

Synonym: 1-Chloromethyl chloroformate; Chloroformic acid chloromethyl ester; Chloromethoxycarbonyl chloride; Chloromethyl carbonochloridate; Chloromethyl chlorocarbonate

CAS Number: 22128-62-7
Empirical Formula (Hill Notation): C2H2Cl2O2
Molecular Weight: 128.94
EC Number: 244-793-3
MDL Number: MFCD00077688
Linear Formula: ClCOOCH2Cl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-23181-10ML 10 mL
$207.00
1/EA
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45-23181-50ML 50 mL
$745.00
1/EA
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assay ≥98.0% (GC)
bp 107-108 °C (lit.)
density 1.450 g/mL at 20 °C
form liquid
InChI 1S/C2H2Cl2O2/c3-1-6-2(4)5/h1H2
InChI key JYWJULGYGOLCGW-UHFFFAOYSA-N
Quality Level 200 
refractive index n20/D 1.428
SMILES string ClCOC(Cl)=O
storage temp. 2-8°C
Application: Chloromethyl chloroformate was used as key reactant in the synthesis of:
• novel aminocarbonyloxymethyl esters of diclofenac and flufenamic acid
• highly water-soluble monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A
• series of 3-acyloxymethyloxycarbonyl-1-aryl-3-methyltriazenes
Packaging: 10, 50 mL in glass bottle
Purity ≥98.0% (GC)
bp 107-108 °C (lit.)
Density 1.450 g/mL at 20 °C
Refractive Index n20/D 1.428
Storage Temp. 2-8°C
UNSPSC 12352100

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