(Diethylamino)sulfur trifluoride
ALDRICH/235253 - 95%
Synonym: DAST; Diethylaminosulfur trifluoride
CAS Number: 38078-09-0
Empirical Formula (Hill Notation): C4H10F3NS
Molecular Weight: 161.19
EC Number: 253-771-2
MDL Number: MFCD00000363
Linear Formula: (C2H5)2NSF3
Product Type: Chemical
| assay | 95% |
| bp | 30-32 °C/3 mmHg (lit.) |
| density | 1.22 g/mL at 25 °C (lit.) |
| form | liquid |
| InChI | 1S/C4H10F3NS/c1-3-8(4-2)9 |
| InChI key | CSJLBAMHHLJAAS-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCN(CC)S(F)(F)F |
| storage temp. | 2-8°C |
| Application: | • Fluorinating agent: reaction with alcohols and carbonyl compounds, Review • Review on nucleophilic fluorination. • Catalyst for Friedel-Crafts allylation using tertiary cyclopropyl silyl ethers and the rearrangement of homoallylic alcohols to unsaturated aldehydes. • Early introduction of a fluoromethyl group stabilizes the epoxide during further manipulations in the synthesis of 26-fluoro-epothilone. • Fluorinating agent for a variety of compounds, including thioethers, alkenols, and cyanohydrins. • Reagent for gem difluorination of ketopipecolinic acids. |
| General description: | Diethylamino sulfur trifluoride (DAST) is a fluorinating reagent used in the synthesis of fluorinated compounds and ring-opening reactions. |
| Packaging: | 1, 5, 25 g in poly bottle |
| Symbol |   GHS02,GHS05 |
| Signal word | Danger |
| Hazard statements | H226 - H242 - H314 |
| Precautionary statements | P210 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P370 + P378 - P403 + P235 |
| Hazard Codes | C |
| Risk Statements | 10-14-20/21/22-34 |
| Safety Statements | 16-26-36/37/39-45 |
| RIDADR | UN3225 - class 4.1 - Self-reactive liquid type D (DIETHYLAMINOSU |
| WGK Germany | WGK 3 |
| Flash Point(F) | 73.4 °F |
| Flash Point(C) | 23 °C |
| Supplemental Hazard Statements | EUH014 |
| Purity | 95% |
| bp | 30-32 °C/3 mmHg (lit.) |
| Density | 1.22 g/mL at 25 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352101 |