2,6-Di-tert-butyl-4-methylpyridine

ALDRICH/249505 - 98%

Synonym: 2,6-Bis(1,1-dimethylethyl)-4-methylpyridine; 2,6-Bis(tert-butyl)-4-methylpyridine; 2,6-Ditert-butyl-4-methylpyridine; 4-Methyl-2,6-di-tert-butylpyridine

CAS Number: 38222-83-2
Empirical Formula (Hill Notation): C₁₄H₂₃N
Molecular Weight: 205.34
EC Number: 253-834-4
MDL Number: MFCD00006305
Linear Formula: C₁₄H₂₃N
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-249505-5G	5 g	$140.00 1/EA	Add To Favorites
45-249505-25G	25 g	$496.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
bp	233 °C (lit.)
form	solid
InChI	1S/C14H23N/c1-10-8-11(13(2,3)4)15-12(9-10)14(5,6)7/h8-9H,1-7H3
InChI key	HVHZEKKZMFRULH-UHFFFAOYSA-N
mp	33-36 °C (lit.)
Quality Level	200
refractive index	n20/D 1.4763 (lit.)
SMILES string	Cc1cc(nc(c1)C(C)(C)C)C(C)(C)C
solubility	ethanol: soluble 5%, clear to slightly hazy, colorless to dark yellow
storage temp.	2-8°C

Application:	2,6-Di-tert-butyl-4-methylpyridine has been used: • in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives • as base in PtCl₄-catalyzed cyclization reactions of homopropargyl azide derivatives • diastereoselective synthesis of β-thiomannopyranosides
General description:	2,6-Di-tert-butyl-4-methylpyridine is a sterically hindered, non-nucleophilic base which distinguishes between BrÖnsted (protonic) and Lewis acids. It also enables the direct high-yield conversion of aldehydes and ketones to vinyl triflates. It inhibits desilylation and hydration of the products during GaCl₃-catalyzed ortho-ethynylation of phenol.
Packaging:	1, 5, 25 g in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315 - H319 - H335
Precautionary statements	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	183.2 °F - closed cup
Flash Point(C)	84 °C - closed cup

Purity	98%
bp	233 °C (lit.)
mp	33-36 °C (lit.)
Refractive Index	n20/D 1.4763 (lit.)
Storage Temp.	2-8°C
UNSPSC	12352100

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