Cyanogen bromide solution
ALDRICH/261610 - 5.0 M in acetonitrile
Synonym: Bromine cyanide; Bromine monocyanide; Bromocyanide; Bromocyanogen; Carbononitridic bromide; Cyanic bromide; Cyanobromide; Cyanogen monobromide
CAS Number: 506-68-3
Empirical Formula (Hill Notation): CBrN
Molecular Weight: 105.92
MDL Number: MFCD00011597
Linear Formula: BrCN
Product Type: Chemical
| concentration | 5.0 M in acetonitrile |
| density | 1.093 g/mL at 25 °C |
| form | liquid |
| InChI | 1S/CBrN/c2-1-3 |
| InChI key | ATDGTVJJHBUTRL-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | BrC#N |
| solubility | alcohol: freely soluble(lit.) |
| diethyl ether: freely soluble(lit.) | |
| water: freely soluble(lit.) | |
| storage temp. | 2-8°C |
| Application: | Cyanogen bromide is a general reagent used to cleave carbon-heteroatom bonds. It is used in the synthesis of organocyanamides from corresponding tertiary amines, which is popularly known as von Braun reaction. CNBr solution is widely used in protein immobilization and cleavage. |
| General description: | Cyanogen bromide solution induces template-guided condensation of oligonucleotides only in the presence of N-substituted morpholines. Mechanism of the phosphomonoester group activation by cyanogen bromide in N-substituted morpholine buffers has been investigated. |
| Packaging: | 100 mL in Sure/Seal™ |
| Symbol |     GHS02,GHS05,GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H225 - H300 + H310 + H330 - H314 - H400 |
| Precautionary statements | P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | F,T+,N |
| Risk Statements | 11-26/27/28-32-34-50/53 |
| Safety Statements | 16-26-28-36/37/39-45-61 |
| RIDADR | UN3489 - class 6.1 - PG 1 - EHS - MP - RQ - acidic - Toxic by in |
| WGK Germany | WGK 3 |
| Flash Point(F) | 42.8 °F - closed cup |
| Flash Point(C) | 6 °C - closed cup |
| Supplemental Hazard Statements | EUH032 |
| Density | 1.093 g/mL at 25 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |