2,6-Difluorobenzaldehyde

ALDRICH/265152 - 98%

CAS Number: 437-81-0
Empirical Formula (Hill Notation): C₇H₄F₂O
Molecular Weight: 142.10
MDL Number: MFCD00010293
Linear Formula: F₂C₆H₃CHO
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-265152-5G	5 g	$29.30 1/EA	Add To Favorites
45-265152-25G	25 g	$140.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
bp	82-84 °C/15 mmHg (lit.)
density	1.317 g/mL at 25 °C (lit.)
form	liquid
functional group	aldehyde
	fluoro
InChI	1S/C7H4F2O/c8-6-2-1-3-7(9)5(6)4-10/h1-4H
InChI key	SOWRUJSGHKNOKN-UHFFFAOYSA-N
mp	15-17 °C (lit.)
Quality Level	100
refractive index	n20/D 1.502 (lit.)
SMILES string	Fc1cccc(F)c1C=O
storage temp.	2-8°C

Application:

2,6-Difluorobenzaldehyde can be used as a reactant to synthesize:
• 5-Cyano-6-(2,6-difluorophenyl)-5,6-dihydro-2-thiouracil via one-pot cyclocondensation reaction with ethyl cyanoacetate and thiourea.
• 1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazole by reacting with 1,2-phenylenediamine in the presence of a catalytic amount of p-toluenesulfonic acid.
• (3E)-4-(2,6-Difluorophenyl)-3-buten-2-one by Wittig olefination reaction with acetylmethylidenetriphenyl phosphorane.
• Methyl 4-fluorobenzo[b]thiophene-2-carboxylate by treating with methyl thioglycolate in the presence of K₂CO₃.

Packaging:

5, 25 g in glass bottle

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	163.4 °F - closed cup
Flash Point(C)	73 °C - closed cup

Purity	98%
bp	82-84 °C/15 mmHg (lit.)
mp	15-17 °C (lit.)
Density	1.317 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.502 (lit.)
Storage Temp.	2-8°C
UNSPSC	12352100

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