4-Aminopyridine
ALDRICH/275875 - ≥99%
Synonym: 4-Pyridinamine; 4-Pyridylamine; 4AP; Fampridine
CAS Number: 504-24-5
Empirical Formula (Hill Notation): C5H6N2
Molecular Weight: 94.11
EC Number: 207-987-9
MDL Number: MFCD00006439
Linear Formula: C5H6N2
Product Type: Chemical
| assay | ≥99% |
| bp | 273 °C (lit.) |
| form | solid |
| InChI | 1S/C5H6N2/c6-5-1-3-7-4-2- |
| InChI key | NUKYPUAOHBNCPY-UHFFFAOYSA |
| mp | 155-158 °C (lit.) |
| Quality Level | 100  |
| SMILES string | Nc1ccncc1 |
| solubility | acetone: soluble(lit.) |
| acetonitrile: soluble(lit.) | |
| DMF: soluble(lit.) | |
| DMSO: soluble(lit.) | |
| ethanol: soluble(lit.) | |
| isopropanol: soluble(lit.) | |
| methanol: soluble(lit.) | |
| THF: soluble(lit.) | |
| water: soluble(lit.) |
| Application: | 4-Aminopyridine can be used as: • A reactant to prepare pharmacologically important 4-amino-N-pyridin-4-yl-butyramide • A reactant to prepare cinnamic acid derivatives as potent cholinesterase inhibitors. • A starting material to prepare aza analogs of batracylin, a topoisomerase II inhibitor. |
| General description: | 4-Aminopyridine (4-AP) blocks the voltage-dependent potassium channels in other nerve membranes. 4-AP is a K+ channel blocker and causes epileptiform activity in in vitro preparations and is a potent convulsant in animals and man. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |    GHS05,GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H300 - H311 + H331 - H314 - H411 |
| Precautionary statements | P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T+ |
| Risk Statements | 28-36/37/38 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2671 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 312.8 °F |
| Flash Point(C) | 156 °C |
| Purity | ≥99% |
| bp | 273 °C (lit.) |
| mp | 155-158 °C (lit.) |
| UNSPSC | 12352100 |