4-Chloro-1-butanol
ALDRICH/278823 - technical grade, ~85%
Synonym: Tetramethylene chlorohydrin
CAS Number: 928-51-8
Empirical Formula (Hill Notation): C4H9ClO
Molecular Weight: 108.57
MDL Number: MFCD00002967
Linear Formula: HO(CH2)4Cl
Product Type: Chemical
| assay | ~85% |
| bp | 84-85 °C/16 mmHg (lit.) |
| density | 1.088 g/mL at 25 °C (lit.) |
| form | liquid |
| functional group | chloro |
| hydroxyl | |
| grade | technical grade |
| InChI | 1S/C4H9ClO/c5-3-1-2-4-6/h |
| InChI key | HXHGULXINZUGJX-UHFFFAOYSA |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | OCCCCCl |
| storage temp. | 2-8°C |
| Application: | 4-Chloro-1-butanol was employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique. |
| General description: | 4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals. |
| Other Notes: | Contains tetrahydrofuran and HCl |
| Packaging: | 50, 250 mL in glass bottle |
| Symbol |    GHS02,GHS05,GHS07 |
| Signal word | Warning |
| Hazard statements | H226 - H290 - H302 - H315 - H319 - H335 |
| Precautionary statements | P210 - P233 - P234 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 10-19-22-36/37/38-40 |
| Safety Statements | 26-36/37-60 |
| RIDADR | UN 2924 8(3) / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 96.8 °F - closed cup |
| Flash Point(C) | 36 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | ~85% |
| bp | 84-85 °C/16 mmHg (lit.) |
| Density | 1.088 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |