2(5H)-Furanone
ALDRICH/283754 - 98%
Synonym: γ-Crotonolactone; 2-Buten-1,4-olide
CAS Number: 497-23-4
Empirical Formula (Hill Notation): C4H4O2
Molecular Weight: 84.07
EC Number: 207-839-3
MDL Number: MFCD00005376
Linear Formula: C4H4O2
Product Type: Chemical
| assay | 98% |
| bp | 86-87 °C/12 mmHg (lit.) |
| density | 1.185 g/mL at 25 °C (lit.) |
| form | liquid |
| functional group | ester |
| InChI | 1S/C4H4O2/c5-4-2-1-3-6-4/ |
| InChI key | VIHAEDVKXSOUAT-UHFFFAOYSA |
| mp | 4-5 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | O=C1OCC=C1 |
| storage temp. | 2-8°C |
| Application: | 2(5H)-Furanone (γ-Crotonolactone) has been used in: • synthesis of (+)-L-733,060, (+)-CP-99,994 and (2S,3R)-3-hydroxypipecolic acid • synthesis of 5-substituted 2(5H) furanones (γ-butenolides) via direct aldol reaction with aromatic aldehydes catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts • Michael addition reactions for synthesis of lignans • three-component Michael-Aldol reactions with an aldehyde anda thiolate or carbanion |
| General description: | Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (γ-crotonolactone) to pyrrolidine. The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains. |
| Packaging: | 1, 5 g in glass bottle |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 213.8 °F - closed cup |
| Flash Point(C) | 101 °C - closed cup |
| Purity | 98% |
| bp | 86-87 °C/12 mmHg (lit.) |
| mp | 4-5 °C (lit.) |
| Density | 1.185 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |