Phosphonoacetic acid
ALDRICH/284270 - 98%
Synonym: (Carboxymethyl)
CAS Number: 4408-78-0
Empirical Formula (Hill Notation): C2H5O5P
Molecular Weight: 140.03
EC Number: 224-558-1
MDL Number: MFCD00004311
Linear Formula: (HO)2P(O)CH2CO2H
Product Type: Chemical
assay | 98% |
form | powder or crystals |
InChI | 1S/C2H5O5P/c3-2(4)1-8(5,6 |
InChI key | XUYJLQHKOGNDPB-UHFFFAOYSA |
mp | 143-146 °C (lit.) |
SMILES string | OC(=O)CP(O)(O)=O |
solubility | water: soluble 100 mg/mL, clear to very slightly hazy, colorless |
Application: | Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner. |
General description: | Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts. It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase in vitro. |
Packaging: | 10, 50 g in glass bottle |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 98% |
mp | 143-146 °C (lit.) |
UNSPSC | 12352100 |