Synonym: (R)-2,2′-Bis[bis(3,5-dimethyl)phosphino]-6,6′-dimethoxy-1,1′-biphenyl; (R)-3,5-Xyl-MeOBIPHEP; SL-A120-1
CAS Number: 394248-45-4
Empirical Formula (Hill Notation): C46H48O2P2
Molecular Weight: 694.82
MDL Number: MFCD09753009
Linear Formula: C46H48O2P2
Product Type: Chemical
| assay |
≥97% (31P-NMR) |
| functional group |
phosphine |
| InChI |
1S/C46H48O2P2/c1-29-17-30(2)22-37(21-29)49(38-23-31(3)18-32(4)24-38)43-15-11-13-41(47-9)45(43)46-42(48-10)14-12-16-44(46)50(39-25-33(5)19-34(6)26-39)40-27-35(7)20-36(8)28-40/h11-28H,1-10H3 |
| InChI key |
IMUHNRWTDUVXOU-UHFFFAOYSA-N |
| optical purity |
ee: ≥99% |
| Quality Level |
100  |
| SMILES string |
COc1cccc(P(c2cc(C)cc(C)c2)c3cc(C)cc(C)c3)c1-c4c(OC)cccc4P(c5cc(C)cc(C)c5)c6cc(C)cc(C)c6 |
| Application: |
(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine] can be used as a ligand:
• In the synthesis of (S)-3-amino-4-methoxy-butan-1-ol, a key starting material for many pharmaceutical drugs.
• In the synthesis of 3-substituted indanones through the reductive Heck reaction of chalcones with various amines.
• In the palladium-catalyzed Tsuji-Trost cyclizations of aldehydes to yield vinylcyclopentane derivatives.
|
| Application: |
Atropisomeric MeOBIPHEP ligands |
| Other Notes: |
sold in collaboration with Solvias AG |
| Packaging: |
1, 5 g in glass bottle |
| Packaging: |
100, 500 mg in glass bottle |
| Packaging: |
Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥97% (31P-NMR) |
| UNSPSC |
12352112 |
