Sodium cyanoborohydride solution
ALDRICH/296813 - 1.0 M in THF
Synonym: Sodium borocyanohydride; Sodium cyanoborohydride; Sodium cyanotrihydroborate
CAS Number: 25895-60-7
Empirical Formula (Hill Notation): CH3BNNa
Molecular Weight: 62.84
MDL Number: MFCD00003516
Linear Formula: NaBH3CN
Product Type: Chemical
25 mL Sure/Seal™ Packaging
| concentration | 1.0 M in THF |
| density | 0.915 g/mL at 25 °C |
| InChI | 1S/CH3BN.Na/c2-1-3;/h2H3; |
| InChI key | CVDUGUOQTVTBJH-UHFFFAOYSA |
| Quality Level | 200  |
| reaction suitability | reagent type: reductant |
| SMILES string | [Na+].[H][B-]([H])([H])C# |
| solubility | alcohol: soluble(lit.) |
| hydrocarbons: insoluble(lit.) | |
| THF: soluble(lit.) | |
| water: soluble(lit.) |
| Application: | Reactant for: • Direct conversion of heterocyclic aldehydes to esters (oxidizing behavior) • Reductive amination reactions • Intramolecular reductive cyclization reactions • Reductions reactions • Preparation of dicyanoborate-based ionic liquids as hypergolic fluids for bipropellants |
| Application: | Sodium cyanoborohydride may be used in the following studies: • As reducing agent for the in vitro radiolabeling of proteins by reductive alkylation. • Reduction of aldehydes and ketones. • Selective deoxygenation of aldehydes and ketones. • Preparation of colloidal gold particles of varying sizes. |
| General description: | Sodium cyanoborohydride is a versatile reducing agent stable in aqueous solution at pH 7.2. It is a weaker reducing agent as compared to NaBH4. It effectively reduces Schiff bases. NaCNBH4 participates in the reductive methylation for the efficient and selective conversion of the e-amino groups of lysyl residues in proteins to the mono- and dimethyl derivatives. |
| Packaging: | 100, 800 mL in Sure/Seal™ |
| Symbol |      GHS02,GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H225 - H260 - H301 + H311 + H331 - H314 - H335 - H336 - H351 - H410 |
| Precautionary statements | P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | F,T,N |
| Risk Statements | 11-19-23/24/25-32-36/37/38-40-50/53 |
| Safety Statements | 16-26-36/37-45-61 |
| RIDADR | UN 1992 6.1(3) / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 1.4 °F - closed cup |
| Flash Point(C) | -17 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Density | 0.915 g/mL at 25 °C |
| UNSPSC | 12352306 |