Di-tert-butylchlorophosphine
ALDRICH/301558 - 96%
Synonym: P, P-bis(1 1-dimethylethyl); Phosphinous chloride
CAS Number: 13716-10-4
Empirical Formula (Hill Notation): C8H18ClP
Molecular Weight: 180.66
MDL Number: MFCD00008815
Linear Formula: [(CH3)3C]2PCl
Product Type: Chemical
| assay | 96% |
| bp | 48 °C/3 mmHg (lit.) |
| density | 0.951 g/mL at 25 °C (lit.) |
| form | liquid |
| functional group | phosphine |
| InChI | 1S/C8H18ClP/c1-7(2,3)10(9 |
| InChI key | MCRSZLVSRGTMIH-UHFFFAOYSA |
| Quality Level | 100  |
| reaction suitability | reagent type: ligand reaction type: Suzuki-Miyaura Coupling |
| refractive index | n |
| SMILES string | CC(C)(C)P(Cl)C(C)(C)C |
| Application: | Di-tert-butylchlorophosphine can be used as a ligand in: • The Pd-catalyzed amination reaction with aryl halides. • The Pd-catalyzed Suzuki-Miyaura cross-coupling of arylboronic acids with aryl bromides and chlorides. |
| General description: | Di-tert-butylchlorophosphine belongs to the class of phosphine ligands. It is used for cross-coupling reactions because of the flexibility of its electronic and steric properties. It plays a key role in stabilizing and activating the central metal atom and is used in reactions such as transition metal-catalyzed C-O, C-N, and C-C bond-forming reactions. |
| Packaging: | 25, 100 g in Sure/Seal™ |
| Packaging: | 5 g in glass bottle |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3265 8 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 143.6 °F - closed cup |
| Flash Point(C) | 62 °C - closed cup |
| Purity | 96% |
| bp | 48 °C/3 mmHg (lit.) |
| Density | 0.951 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352001 |