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2-Cyanoethyl N,N-diisopropylchlorophosphoramidite

ALDRICH/302309 - Cl 13.5-15.5 %

Synonym: Chloro(diisopropylamino)-β-cyanoethoxyphosphine

CAS Number: 89992-70-1
Empirical Formula (Hill Notation): C9H18ClN2OP
Molecular Weight: 236.68
MDL Number: MFCD00011544
Linear Formula: [(CH3)2CH]2NP(Cl)OCH2CH2CN
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-302309-250MG 250 mg
$39.10
1/EA
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45-302309-1G 1 g
$91.10
1/EA
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45-302309-5G 5 g
$308.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 302309-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 302309-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 302309-250MG

 

composition Cl, 13.5-15.5%
density 1.061 g/mL at 25 °C (lit.)
form liquid
InChI 1S/C9H18ClN2OP/c1-8(2)12(9(3)4)14(10)13-7-5-6-11/h8-9H,5,7H2,1-4H3
InChI key QWTBDIBOOIAZEF-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC(C)N(C(C)C)P(Cl)OCCC#N
storage temp. −20°C
Application: 2-Cyanoethyl N,N-diisopropylchlorophosphoramidite was employed:
• for selective monophosphorylation of carbohydrates and nucleosides
• for conversion of protected ribonucleosides to phosphoramidites
• as phosphitylating reagent for 3′-hydroxyl groups in the synthesis of oligodeoxyribonucleotides
• in a scalable, solution-phase oligonucleotide synthesis employing phosphoramidite chemistry and DMT-, iBu- and Bz-protected monomers. Intermediates were isolated by extraction without further purification
Packaging: 1, 5 g in glass bottle
Packaging: 250 mg in glass bottle
Density 1.061 g/mL at 25 °C (lit.)
Storage Temp. −20°C
UNSPSC 12352100

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