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Methyl 2-acetamidoacrylate

ALDRICH/317519 - 98%

CAS Number: 35356-70-8
Empirical Formula (Hill Notation): C6H9NO3
Molecular Weight: 143.14
MDL Number: MFCD00013394
Linear Formula: H2C=C(NHCOCH3)CO2CH3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-317519-5G 5 g
$285.00
1/EA
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assay 98%
bp 104 °C/8 mmHg (lit.)
InChI 1S/C6H9NO3/c1-4(6(9)10-3)7-5(2)8/h1H2,2-3H3,(H,7,8)
InChI key SMWNFFKPVLVOQQ-UHFFFAOYSA-N
mp 50-52 °C (lit.)
SMILES string COC(=O)C(=C)NC(C)=O
Application: Methyl 2-acetamidoacrylate can undergo [2+2] cycloaddition (Michael–Dieckmann-type reaction) with ketene diethyl acetal to yield the cyclobutane core. It may be used in rhodium-catalyzed 2-alkenylpyrrole formation.
General description: Conjugated addition of secondary amines, imidazole and pyrazole to methyl 2 methyl 2-acetamidoacrylate in the presence of a catalyst results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives. Methyl-2-acetamidoacrylate (M2AA) is an anti-inflammatory agent. The catalytic reaction of methyl 2-acetamidoacrylate with Grignard’s reagents affords α-amino esters. M2AA can form thermosensitive copolymers with methyl acrylate.
General description: Methyl ester of 2-acetamidoacrylate . methyl 2-acetamidoacrylate (Me-2-AA) is a di-unsaturated α-amino acid derivative. methyl-2-acetamidoacrylate exihibits anti -inflammatory properties, it is very effective against lipopolysaccharide (LPS)- induced nitric oxide production by RAW 264.
Packaging: 1, 5 g in glass bottle
Purity 98%
bp 104 °C/8 mmHg (lit.)
mp 50-52 °C (lit.)
UNSPSC 12162002

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