Dimethyl sulfate
ALDRICH/320293 - ≥99%
Synonym: Sulfuric acid dimethyl ester
CAS Number: 77-78-1
Empirical Formula (Hill Notation): C2H6O4S
Molecular Weight: 126.13
EC Number: 201-058-1
MDL Number: MFCD00008416
Linear Formula: (CH3O)2SO2
Product Type: Chemical
| assay | ≥99% |
| autoignition temp. | 923 °F |
| bp | 188 °C (lit.) |
| density | 1.333 g/mL at 25 °C (lit.) |
| form | liquid |
| InChI | 1S/C2H6O4S/c1-5-7(3,4)6-2 |
| InChI key | VAYGXNSJCAHWJZ-UHFFFAOYSA |
| mp | −32 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | COS(=O)(=O)OC |
| vapor density | 4.3 (vs air) |
| vapor pressure | 0.7 mmHg ( 25 °C) |
| Application: | Dimethyl sulfate is a powerful methylating reagent for the methylation of carboxylic acids, alcohols, phenols, lactams, oximes, hydroxylamines, and hydroperoxides. It can be used as a reagent for the preparation of N-methyl alkyl- and aryl-substituted amines, amides, and quaternary ammonium salts. Dimethyl sulfate is also used in the methylation of sulfur-containing compounds to synthesize sulfides and sulfonium ions. It can also be used as a reagent: • For the preparation of quaternary ammonium acrylic monomer as a potent antibacterial agent by the quaternization of 2-dimethylamino ethyl methacrylate. • Along with dimethyl sulfoxide for the synthesis of epoxides from aldehydes and ketones via formation of trimethylsulfonium cation. • To prepare an oxygenate additive for diesel by the methylation of glycerol. |
| Packaging: | 1 L in Sure/Seal™ |
| Symbol |    GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301 - H314 - H317 - H330 - H341 - H350 |
| Precautionary statements | P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T+ |
| Risk Statements | 45-25-26-34-43-68 |
| Safety Statements | 53-45-61 |
| RIDADR | UN1595 - class 6.1 - PG 1 - Dimethyl sulphate |
| WGK Germany | WGK 3 |
| Flash Point(F) | 181.4 °F - closed cup |
| Flash Point(C) | 83 °C - closed cup |
| Purity | ≥99% |
| bp | 188 °C (lit.) |
| mp | −32 °C (lit.) |
| Density | 1.333 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352108 |