Trimethylphosphine
ALDRICH/323322 - 97%
Synonym: PMe3
CAS Number: 594-09-2
Empirical Formula (Hill Notation): C3H9P
Molecular Weight: 76.08
EC Number: 209-823-1
MDL Number: MFCD00008510
Linear Formula: (CH3)3P
Product Type: Chemical
| assay | 97% |
| bp | 38-40 °C (lit.) |
| density | 0.738 g/mL at 20 °C (lit.) |
| form | liquid |
| functional group | phosphine |
| InChI | 1S/C3H9P/c1-4(2)3/h1-3H3 |
| InChI key | YWWDBCBWQNCYNR-UHFFFAOYSA |
| mp | −86 °C (lit.) |
| Quality Level | 200  |
| reaction suitability | reaction type: Buchwald-Hartwig Cross Coupling Reaction |
| reaction type: Heck Reaction | |
| reaction type: Hiyama Coupling | |
| reaction type: Negishi Coupling | |
| reaction type: Sonogashira Coupling | |
| reaction type: Stille Coupling | |
| reaction type: Suzuki-Miyaura Coupling | |
| reagent type: ligand reaction type: Mitsunobu Reaction |
|
| reagent type: ligand reaction type: Wittig Reaction |
|
| refractive index | n |
| SMILES string | CP(C)C |
| storage temp. | 2-8°C |
| vapor pressure | 7.24 psi ( 20 °C) |
| Application: | Trimethylphosphine (PMe3) is an electron-rich phosphine ligand used as a reagent in Mitsunobu reaction. It can be used: • In transformation of azides into carbamates; aziridines to azidoalcohols; and ketoximes to ketones with 2,2 • In Aza-Wittig reaction;, C-H bond activation of imines; cross-coupling reactions. • In the preparation of (cyanomethylene) trimethylphosphorane (CMMP) which is used as a reagent in Mitsunobu type reaction. • As a reagent in the synthesis of ruthenium trimethylphosphine complexes, which in turn are used as catalysts for hydrogenation of CO2 to formic acid. |
| Packaging: | 25 g in Sure/Seal™ |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H315 - H319 - H335 |
| Precautionary statements | P210 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-36/37/38 |
| Safety Statements | 9-16-26-36/37/39 |
| RIDADR | UN 1993BE 3 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | -2.2 °F - closed cup |
| Flash Point(C) | -19 °C - closed cup |
| Purity | 97% |
| bp | 38-40 °C (lit.) |
| mp | −86 °C (lit.) |
| Density | 0.738 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352128 |