Lithium (trimethylsilyl)acetylide solution
ALDRICH/335452 - 0.5 M in THF
Synonym: (Trimethylsilyl)
CAS Number: 54655-07-1
Empirical Formula (Hill Notation): C5H9LiSi
Molecular Weight: 104.15
MDL Number: MFCD00075059
Linear Formula: (CH3)3SiC≡CLi
Product Type: Chemical
25 mL Sure/Seal™ Packaging
| concentration | 0.5 M in THF |
| density | 0.88 g/mL at 25 °C |
| form | liquid |
| InChI | 1S/C5H9Si.Li/c1-5-6(2,3)4 |
| InChI key | ZVXXEONXFWSCIZ-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | [Li]C#C[Si](C)(C)C |
| Application: | Lithium (trimethylsilyl)acetylide can be used as a reagent: • In the transmetalation and nucleophilic displacement reactions. • To prepare propargylic alcohol derivatives by reacting with aldehydes and ketones. • To synthesize α,βynones by treating with Weinreb amide or with isoxazolidide. • Along with Grignard reagent to convert γ- and δ-thiolactams to thioiminium salts, which are employed as key intermediates to produce disubstituted pyrrolidines. |
| Application: | Reacts with halotriazines to produce conductive, anisotropic carbon-nitrogen materials. |
| Legal Information: | Sure/Seal is a trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 4×25, 50, 500 mL in Sure/Seal™ |
| Packaging: | The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product. |
| Symbol |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H314 - H335 - H351 |
| Precautionary statements | P210 - P260 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37/38-40 |
| Safety Statements | 16-26-36/37 |
| RIDADR | UN 2924 8(3) / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | -9.4 °F - closed cup |
| Flash Point(C) | -23 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Density | 0.88 g/mL at 25 °C |
| UNSPSC | 12352103 |